Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.42 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.42 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.42 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.42 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.42 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.42 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.42 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318630 | 0.91 | MMEL1 (0.53) | MMEL1CTSLCTSSADCY6ADCY3 | |
| SCHEMBL7314722 | 0.91 | MMEL1 (0.53) | MMEL1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL7310804 | 0.90 | MMEL1 (0.58) | MMEL1 | |
| SCHEMBL7309973 | 0.90 | MMEL1 (0.58) | MMEL1 | |
| SCHEMBL7312208 | 0.90 | MMEL1 (0.58) | MMEL1 | |
| SCHEMBL7316440 | 0.89 | MMEL1 (0.50) | MMEL1CTSLCTSSADCY6ADCY3 | |
| SCHEMBL7309952 | 0.87 | MMEL1 (0.53) | MMEL1CTSLCTSS | |
| SCHEMBL7308199 | 0.87 | MMEL1 (0.50) | MMEL1CTSLCTSSADCY6ADCY3 | |
| SCHEMBL7311806 | 0.86 | MMEL1 (0.51) | MMEL1ADCY6ADCY3ADCY9ADCY5 | |
| SCHEMBL7318912 | 0.86 | MMEL1 (0.51) | MMEL1ADCY6ADCY3ADCY9ADCY5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |