Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312542 | 0.95 | CCKBR (0.74) | CCKBRKCNH2 | |
| SCHEMBL7312866 | 0.86 | CCKBR (0.67) | CCKBRKCNH2 | |
| L-365260 SCHEMBL31616010 | 0.84 | CCKBR (1.00) | CCKBRKCNH2 | |
| L-365260 SCHEMBL29694194 | 0.84 | CCKBR (1.00) | CCKBRKCNH2 | |
| L-365260 SCHEMBL5931098 | 0.84 | CCKBR (1.00) | CCKBRKCNH2 | |
| L-365260 SCHEMBL9843248 | 0.84 | CCKBR (1.00) | CCKBRKCNH2 | |
| L-365260 SCHEMBL29403509 | 0.84 | CCKBR (1.00) | CCKBRKCNH2 | |
| L-365260 SCHEMBL31616154 | 0.84 | CCKBR (1.00) | CCKBRKCNH2 | |
| L-365260 SCHEMBL1650330 | 0.84 | CCKBR (1.00) | CCKBRKCNH2 | |
| SCHEMBL9865274 | 0.83 | CCKBR (0.88) | CCKBRKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5798353-A | Polysubstituted 3-acylamino-5-phenyl-1,4-benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them | SANOFI (FR) | 1998-08-25 | — | — | US | disclosed |
| US-5719143-A | Polysubstituted 3-acylamino-5-phenyl-1, 4-benzodiazepin-2-one derivatives, process for their preparation and the pharmaceutical compositions containing them | SANOFI (FR) | 1998-02-17 | — | — | US | disclosed |
| EP-0667344-A1 | 3-acylamino-5-(polysubstituted phenyl)-1,4-benzodiazepin-2-ones useful as CCK-receptor agonists | SANOFI (FR) | 1995-08-16 | — | — | EP | disclosed |