Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458911 | 0.92 | AKR1C3 (0.64) | MAPTALDH1A1POLBAKR1C3AKR1C1 | |
| SCHEMBL12793334 | 0.89 | MAPT (0.80) | MAPTALDH1A1AKR1C3AKR1C1RAB9A | |
| SCHEMBL19392388 | 0.89 | MAPT (0.80) | MAPTALDH1A1AKR1C3AKR1C1RAB9A | |
| SCHEMBL25293495 | 0.89 | MAPT (0.80) | MAPTALDH1A1AKR1C3AKR1C1RAB9A | |
| SCHEMBL10282884 | 0.88 | ALDH1A1 (0.70) | MAPTALDH1A1POLBRAB9ALMNA | |
| SCHEMBL14538823 | 0.88 | ALDH1A1 (0.70) | MAPTALDH1A1POLBRAB9ALMNA | |
| SCHEMBL4701073 | 0.87 | MAPT (0.77) | MAPTALDH1A1AKR1C3AKR1C1LMNA | |
| SCHEMBL21669903 | 0.87 | MAPT (0.77) | MAPTALDH1A1AKR1C3AKR1C1LMNA | |
| SCHEMBL610121 | 0.87 | MAPT (0.77) | MAPTALDH1A1AKR1C3AKR1C1LMNA | |
| SCHEMBL25288750 | 0.86 | MAPT (0.76) | MAPTALDH1A1AKR1C3AKR1C1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1336930-A | Bridged heterocyclic derivatives | GPINIL HOLDING CORP (US) | 2002-02-20 | — | — | CN | disclosed |
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |