Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 10/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 10/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | PTAFR | P25105 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PDE1A | P54750 | 1/20 | 0.48 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302908 | 0.91 | PDE3B (0.53) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7315971 | 0.85 | PDE3B (0.52) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7304090 | 0.84 | KDM4E (0.43) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7313626 | 0.83 | PDE3B (0.65) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7306060 | 0.83 | PDE3B (0.65) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7318197 | 0.82 | PDE3B (0.64) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7312406 | 0.82 | PDE3B (0.43) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7303943 | 0.81 | ALDH1A1 (0.53) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5811108 | 0.81 | PDE3B (0.69) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7317196 | 0.81 | PDE3B (0.61) | PDE3BPDE3AALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |