Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 7/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309212 | 0.89 | PDE3B (0.43) | KCNA5PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL7311363 | 0.87 | KCNA5 (0.41) | KCNA5PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL7313662 | 0.87 | KCNA5 (0.46) | KCNA5PDE3BPDE3AMAOBALDH1A1 | |
| SCHEMBL7317323 | 0.85 | KCNA5 (0.45) | KCNA5PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL7309122 | 0.84 | KCNA5 (0.49) | KCNA5MAOBALDH1A1TSHRMEN1 | |
| SCHEMBL7318369 | 0.83 | ALDH1A1 (0.43) | KCNA5PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL7306732 | 0.80 | PDE3B (0.46) | KCNA5PDE3BPDE3AALDH1A1TSHR | |
| SCHEMBL7313419 | 0.80 | PDE3B (0.48) | PDE3BPDE3AMAOBALDH1A1KDM4E | |
| SCHEMBL7308523 | 0.78 | PDE3B (0.43) | KCNA5PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL7312711 | 0.78 | ALDH1A1 (0.42) | KCNA5PDE3BPDE3AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |