Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7343779 | 0.99 | REN (0.87) | REN | |
| SCHEMBL7296837 | 0.93 | REN (0.76) | REN | |
| SCHEMBL7300532 | 0.93 | REN (0.98) | REN | |
| SCHEMBL6044703 | 0.93 | REN (0.98) | REN | |
| Hydrochloric Acid SCHEMBL7310044 | 0.92 | REN (0.78) | REN | |
| Hydrochloric Acid SCHEMBL7305291 | 0.92 | REN (1.00) | REN | |
| Hydrochloric Acid SCHEMBL7300882 | 0.92 | REN (1.00) | REN | |
| SCHEMBL8260192 | 0.90 | REN (0.85) | REN | |
| SCHEMBL8238828 | 0.90 | REN (0.85) | REN | |
| SCHEMBL14098298 | 0.90 | REN (0.85) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0678503-B1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | NOVARTIS AG (CH) | 1999-09-01 | — | — | EP | claimed |
| EP-0678503-A1 | Delta-amino-gamma-hydroxy-omega-aryl alkanoic acid amides with enzyme especially renin inhibiting activities | CIBA-GEIGY AG (CH) | 1995-10-25 | — | — | EP | claimed |