SCHEMBL7309345

SCHEMBL7309345

CC1CCN(C(=O)C(N)CCCCc2ccccn2)CC1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 4/20 0.43
DPP4 P27487 1/20 0.43
OGA O60502 1/20 0.42
DPP8 Q6V1X1 1/20 0.42
DPP9 Q86TI2 1/20 0.42
HRH3 Q9Y5N1 2/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
TP53 P04637 1/20 0.40
HRH1 P35367 1/20 0.40
NAAA Q02083 1/20 0.39
MEN1 O00255 1/20 0.39
GAA P10253 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7309335 1.00 DPP7 (0.43) DPP7DPP4OGADPP8DPP9
SCHEMBL7316767 0.83 POLB (0.47) DPP7KDM4EALDH1A1HPGDMEN1
SCHEMBL7316773 0.83 POLB (0.47) DPP7KDM4EALDH1A1HPGDMEN1
SCHEMBL7331189 0.81 F2 (0.56) DPP7DPP4DPP8DPP9KDM4E
SCHEMBL6605447 0.80 F2 (0.39) DPP7DPP4DPP8DPP9ALDH1A1
Hydrochloric Acid SCHEMBL6543323 0.79 F2 (0.41) DPP7DPP4DPP8DPP9ALDH1A1
SCHEMBL7330876 0.77 DPP7 (0.44) DPP7DPP4OGADPP8DPP9
SCHEMBL7330894 0.77 DPP7 (0.44) DPP7DPP4OGADPP8DPP9
SCHEMBL15936083 0.77 ALDH1A1 (0.48) OGAKDM4EALDH1A1HPGDTP53
SCHEMBL1337304 0.76 HPGD (0.56) DPP7ALDH1A1HPGDHRH1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5332822-A Anticoagulants BRISTOL-MYERS SQUIBB COMPANY (US) 1994-07-26 US disclosed