Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 4/20 | 0.55 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.55 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4734665 | 0.95 | SLC6A4 (0.60) | SLC6A9SLC6A4HRH3UTS2R | |
| Oxalic Acid SCHEMBL7309230 | 0.87 | SLC6A4 (0.53) | SLC6A9SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL7302789 | 0.86 | SLC6A4 (0.62) | SLC6A9SLC6A4HRH3UTS2R | |
| Oxalic Acid SCHEMBL7310180 | 0.84 | FFAR1 (0.52) | SLC6A9SLC6A4 | |
| Oxalic Acid SCHEMBL7308452 | 0.83 | KDM4E (0.61) | SLC6A9SLC6A4HRH3UTS2R | |
| Oxalic Acid SCHEMBL7313016 | 0.83 | SLC6A9 (0.72) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL4735200 | 0.83 | SLC6A4 (0.56) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL5270870 | 0.82 | SLC6A4 (0.70) | SLC6A9SLC6A4HRH3 | |
| SCHEMBL7158810 | 0.82 | SLC6A4 (0.73) | SLC6A9SLC6A4HRH3 | |
| Oxalic Acid SCHEMBL5142654 | 0.82 | SLC6A9 (0.68) | SLC6A9SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4626549-A | Treatment of obesity with aryloxyphenylpropylamines | ELI LILLY AND COMPANY (US) | 1986-12-02 | — | — | US | disclosed |
| US-4314081-A | ANTIDEPRESSANTS | ELI LILLY AND COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4194009-A | ANTIDEPRESSANT | ELI LILLY AND COMPANY (US) | 1980-03-18 | — | — | US | disclosed |
| US-4018895-A | Aryloxyphenylpropylamines in treating depression | ELI LILLY AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |