Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.47 |
| ▸ | CTSB | P07858 | 6/20 | 0.47 |
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309637 | 1.00 | CTSL (0.47) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7303674 | 0.89 | CTSL (0.54) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7303685 | 0.89 | CTSL (0.54) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7307431 | 0.89 | CTSL (0.45) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7307443 | 0.89 | CTSL (0.45) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7309486 | 0.88 | CTSL (0.47) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7309500 | 0.88 | CTSL (0.47) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7309644 | 0.88 | CTSL (0.39) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7310190 | 0.85 | CTSL (0.48) | CTSLCTSBCTSKMMP3CTSS | |
| SCHEMBL7310207 | 0.85 | CTSL (0.48) | CTSLCTSBCTSKMMP3CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0525420-A1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | Mitsubishi Chemical Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |