Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8293222 | 0.79 | ALDH1A1 (0.36) | NISCH | |
| SCHEMBL12984928 | 0.65 | — | — | |
| SCHEMBL1685395 | 0.64 | NISCH (0.31) | NISCH | |
| SCHEMBL196583 | 0.59 | ALDH1A1 (0.33) | — | |
| SCHEMBL5059055 | 0.59 | NISCH (0.39) | NISCH | |
| SCHEMBL1097893 | 0.58 | — | — | |
| SCHEMBL533283 | 0.57 | NISCH (0.67) | NISCH | |
| SCHEMBL27721370 | 0.57 | SCN5A (0.37) | — | |
| SCHEMBL208526 | 0.57 | ALDH1A1 (0.35) | — | |
| SCHEMBL17200849 | 0.57 | ALDH1A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | claimed |
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |