Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 16/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 16/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307703 | 0.80 | PDE3B (0.45) | PDE3BPDE3ANPC1JAK2RAB9A | |
| SCHEMBL7311995 | 0.79 | PDE3B (0.71) | PDE3BPDE3A | |
| SCHEMBL7317488 | 0.76 | PDE3B (0.47) | PDE3BPDE3A | |
| SCHEMBL7309559 | 0.75 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7307753 | 0.75 | PDE3B (0.48) | PDE3BPDE3A | |
| SCHEMBL7310848 | 0.75 | PDE3B (0.52) | PDE3BPDE3A | |
| SCHEMBL7316912 | 0.75 | PDE3B (0.63) | PDE3BPDE3A | |
| SCHEMBL7318780 | 0.74 | PDE3B (0.69) | PDE3BPDE3A | |
| SCHEMBL7312198 | 0.73 | PDE3B (0.44) | PDE3BPDE3ANPC1RAB9ATHRB | |
| SCHEMBL7317765 | 0.73 | PDE3B (0.73) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |