SCHEMBL7310848

SCHEMBL7310848

Cc1cc(OCCCCC(=O)N(C)Cc2ccccc2)cc2c1N=C1NC(=O)C(CO)N1C2

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 19/20 0.52
PDE3A Q14432 19/20 0.52
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7309559 0.86 PDE3B (0.52) PDE3BPDE3A
SCHEMBL7318826 0.85 PDE3B (0.58) PDE3BPDE3A
SCHEMBL7312088 0.83 PDE3B (0.46) PDE3BPDE3AMEN1KMT2A
SCHEMBL7312634 0.81 PDE3B (0.44) PDE3BPDE3AMEN1KMT2A
SCHEMBL7318939 0.80 PDE3B (0.50) PDE3BPDE3A
SCHEMBL7313823 0.78 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7310542 0.78 PDE3B (0.50) PDE3BPDE3AMEN1KMT2A
SCHEMBL7317020 0.78 PDE3B (0.51) PDE3BPDE3A
SCHEMBL7307753 0.77 PDE3B (0.48) PDE3BPDE3A
SCHEMBL7316240 0.77 PDE3B (0.71) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed