Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.59 |
| ▸ | KIF11 | P52732 | 10/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242023 | 0.84 | EBP (0.59) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5237762 | 0.84 | EBP (0.59) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL8751165 | 0.84 | EBP (0.59) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5236598 | 0.84 | EBP (0.59) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL5226760 | 0.81 | EBP (0.56) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7753625 | 0.81 | EBP (0.56) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7316917 | 0.81 | EBP (0.56) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7316926 | 0.81 | EBP (0.56) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7307228 | 0.80 | EBP (0.55) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL7304642 | 0.79 | EBP (0.54) | EBPSIGMAR1L3MBTL1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |