Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 4/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310211 | 1.00 | KLK7 (0.50) | KLK7PPARACACNA1BCTSSPPARG | |
| SCHEMBL7303397 | 0.88 | KLK7 (0.50) | KLK7PPARACTSSPPARGSYK | |
| SCHEMBL7303403 | 0.88 | KLK7 (0.50) | KLK7PPARACTSSPPARGSYK | |
| SCHEMBL7304843 | 0.86 | KLK7 (0.54) | KLK7PPARACTSSPPARGSYK | |
| SCHEMBL7308969 | 0.85 | CACNA1B (0.53) | KLK7PPARACACNA1BCTSSPPARG | |
| SCHEMBL7308965 | 0.85 | CACNA1B (0.53) | KLK7PPARACACNA1BCTSSPPARG | |
| SCHEMBL17464243 | 0.85 | KLK7 (0.65) | KLK7PPARACTSSPPARGSYK | |
| SCHEMBL12873043 | 0.85 | KLK7 (0.65) | KLK7PPARACTSSPPARGSYK | |
| SCHEMBL30788980 | 0.83 | CTSK (0.54) | KLK7PPARACTSSPPARGSYK | |
| SCHEMBL24205792 | 0.82 | PPARA (0.56) | KLK7PPARACACNA1BCTSSPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0520336-A2 | Aldehyde derivatives and their use as calpain inhibitors | FUJIREBIO Inc. (JP) | 1992-12-30 | — | — | EP | disclosed |