Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 6/20 | 0.51 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305444 | 0.89 | HTR2B (0.50) | HTR2BCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7307896 | 0.87 | HTR2B (0.46) | HTR2BITGB3ITGA2BHSD17B10SIGMAR1 | |
| SCHEMBL7303482 | 0.87 | HTR2B (0.48) | HTR2BCACNA2D1CACNA1BCACNB1CACNA1C | |
| SCHEMBL7308689 | 0.87 | HTR2B (0.54) | HTR2BITGB3ITGA2BSIGMAR1PARP2 | |
| SCHEMBL7313924 | 0.85 | HTR2B (0.51) | HTR2BCACNA2D1CACNA1BCACNB1ITGB3 | |
| SCHEMBL7315337 | 0.84 | HTR2B (0.47) | HTR2BITGB3ITGA2B | |
| SCHEMBL7311844 | 0.82 | HTR2B (0.44) | HTR2B | |
| SCHEMBL7305604 | 0.82 | HTR2B (0.56) | HTR2BALDH1A1SIGMAR1 | |
| SCHEMBL7301029 | 0.82 | HTR2B (0.43) | HTR2BSIGMAR1 | |
| SCHEMBL7311678 | 0.81 | HTR2B (0.45) | HTR2BITGB3ITGA2BHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711770-A1 | Antagonists of adhesion receptors | MERCK PATENT GmbH (DE) | 1996-05-15 | — | — | EP | disclosed |