Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305278 | 0.95 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL7310230 | 0.92 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL7307401 | 0.87 | AGTR1 (0.51) | AGTR1AGTR2 | |
| SCHEMBL684076 | 0.85 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL7298105 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL94599 | 0.84 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL7835576 | 0.83 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7299577 | 0.83 | PPARG (0.60) | — | |
| Olmesartan SCHEMBL94037 | 0.82 | AGTR1 (0.73) | AGTR1AGTR2 | |
| Olmesartan SCHEMBL29368106 | 0.82 | AGTR1 (0.73) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545912-B1 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 2001-04-25 | — | — | EP | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0545912-A2 | 1-Biphenylmethylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1993-06-09 | — | — | EP | disclosed |
| EP-0503785-A1 | 1-Biphenylimidazole derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1992-09-16 | — | — | EP | disclosed |