Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375879 | 0.87 | PDE3B (0.36) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL10375063 | 0.86 | MAPK1 (0.37) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL10376966 | 0.86 | MAPK1 (0.37) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL10376980 | 0.85 | PDE3B (0.36) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL7308660 | 0.85 | MEN1 (0.37) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL10376744 | 0.84 | PDE3B (0.38) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL10376003 | 0.84 | PDE3B (0.36) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL7320463 | 0.84 | PDE3B (0.36) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT | |
| SCHEMBL7310679 | 0.84 | PDE3B (0.38) | ALDH1A1PDE3BPDE3AMAPTPDE4A | |
| SCHEMBL10376684 | 0.82 | PDE3B (0.38) | SMN1; SMN2ALDH1A1PDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |