Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.40 |
| ▸ | PDE2A | O00408 | 6/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320585 | 0.98 | PDE3B (0.42) | PDE3BPDE3APDE2AP2RY12PPARG | |
| SCHEMBL7310966 | 0.97 | PDE3B (0.43) | PDE3BPDE3APDE2AP2RY12PPARG | |
| SCHEMBL7315486 | 0.93 | PDE3B (0.43) | PDE3BPDE3APDE2AP2RY12PPARG | |
| SCHEMBL7310371 | 0.90 | PDE3B (0.42) | PDE3BPDE3APDE2AP2RY12PPARG | |
| SCHEMBL10375826 | 0.89 | PDE3B (0.47) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7307410 | 0.87 | PDE3B (0.41) | PDE3BPDE3APDE2AP2RY12PPARG | |
| SCHEMBL10374533 | 0.87 | PDE3B (0.50) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7318488 | 0.86 | PDE3B (0.42) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7321124 | 0.85 | PDE3B (0.43) | PDE3BPDE3APDE2AP2RY12PPARG | |
| SCHEMBL7312013 | 0.85 | PDE3B (0.41) | PDE3BPDE3APDE2AP2RY12PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |