Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 18/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 18/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 10/20 | 0.41 |
| ▸ | PDE2A | O00408 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307410 | 0.98 | PDE3B (0.41) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL7319718 | 0.95 | PDE3B (0.43) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL7306577 | 0.92 | PDE3B (0.44) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL7316875 | 0.92 | PDE3B (0.42) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL10376014 | 0.91 | PDE3B (0.41) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL10377093 | 0.91 | PDE3B (0.43) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL10376785 | 0.90 | PDE3B (0.47) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL10376853 | 0.90 | PDE3B (0.48) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL10376932 | 0.89 | PDE3B (0.44) | PDE3BPDE3AP2RY12PDE2AHPGD | |
| SCHEMBL10374494 | 0.89 | PDE3B (0.47) | PDE3BPDE3AP2RY12PDE2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |