Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.47 |
| ▸ | CFD | P00746 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 5/20 | 0.41 |
| ▸ | BIRC3 | Q13489 | 5/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 5/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305140 | 0.92 | TACR1 (0.44) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7314427 | 0.88 | TACR1 (0.46) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7314908 | 0.86 | TACR1 (0.49) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7308853 | 0.85 | TACR1 (0.46) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7308856 | 0.85 | TACR1 (0.46) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7308379 | 0.82 | TACR1 (0.44) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7317377 | 0.82 | TACR1 (0.44) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL8083547 | 0.82 | TACR1 (0.44) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7308390 | 0.82 | TACR1 (0.44) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7303981 | 0.82 | TACR1 (0.44) | TACR1CFDDPP8DPP7XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |