Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.44 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | XIAP | P98170 | 5/20 | 0.42 |
| ▸ | BIRC3 | Q13489 | 5/20 | 0.42 |
| ▸ | BIRC2 | Q13490 | 5/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308390 | 1.00 | TACR1 (0.44) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7308379 | 1.00 | TACR1 (0.44) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7309067 | 0.93 | ACE (0.41) | DPP8DPP7ACEF2PRSS1 | |
| SCHEMBL7309074 | 0.93 | ACE (0.41) | DPP8DPP7ACEF2PRSS1 | |
| SCHEMBL7319269 | 0.89 | TACR1 (0.41) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7317505 | 0.89 | TACR1 (0.41) | TACR1CFDDPP8DPP7XIAP | |
| SCHEMBL7316700 | 0.88 | F2 (0.42) | DPP8XIAPACEF2PRSS1 | |
| SCHEMBL7316690 | 0.88 | F2 (0.42) | DPP8XIAPACEF2PRSS1 | |
| SCHEMBL7307561 | 0.88 | ACE (0.38) | ACEF2PRSS1DPP4 | |
| SCHEMBL7306125 | 0.87 | ACE (0.48) | DPP8ACEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |