Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318697 | 0.93 | EBP (0.35) | SIGMAR1EBPEPHX1ALDH1A1DPP4 | |
| SCHEMBL7301361 | 0.91 | EBP (0.45) | SIGMAR1EBPHTR2ALMNACACNA1B | |
| SCHEMBL7305480 | 0.88 | EBP (0.44) | SIGMAR1EBPEPHX1CACNA1B | |
| SCHEMBL7309523 | 0.87 | EBP (0.43) | SIGMAR1EBPEPHX1CACNA1B | |
| SCHEMBL7316069 | 0.84 | EBP (0.38) | SIGMAR1EBPEPHX1DPP4DPP8 | |
| SCHEMBL7308551 | 0.84 | EBP (0.37) | SIGMAR1EBPCACNA1B | |
| SCHEMBL7306036 | 0.84 | EBP (0.41) | SIGMAR1EBPCACNA1B | |
| SCHEMBL7316565 | 0.84 | EBP (0.37) | SIGMAR1EBPCACNA1B | |
| SCHEMBL7315116 | 0.83 | EBP (0.36) | SIGMAR1EBPCACNA1B | |
| SCHEMBL7311070 | 0.83 | CACNA1B (0.38) | SIGMAR1EBPHTR2AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |