Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.30 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309523 | 0.97 | EBP (0.43) | EBPSIGMAR1CHRM3CHRM2CACNA1B | |
| SCHEMBL7301361 | 0.96 | EBP (0.45) | EBPSIGMAR1CHRM3CHRM2CACNA1B | |
| SCHEMBL7306036 | 0.91 | EBP (0.41) | EBPSIGMAR1CHRM3CACNA1B | |
| SCHEMBL7316565 | 0.91 | EBP (0.37) | EBPSIGMAR1CHRM3CACNA1B | |
| SCHEMBL7308551 | 0.90 | EBP (0.37) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7316069 | 0.88 | EBP (0.38) | EBPSIGMAR1CHRM3EPHX1GRM2 | |
| SCHEMBL7310779 | 0.88 | SIGMAR1 (0.38) | EBPSIGMAR1CACNA1BEPHX1 | |
| SCHEMBL7315116 | 0.87 | EBP (0.36) | EBPSIGMAR1CACNA1B | |
| SCHEMBL7311070 | 0.87 | CACNA1B (0.38) | EBPSIGMAR1CHRM3CHRM2CACNA1B | |
| SCHEMBL7302652 | 0.87 | EBP (0.37) | EBPSIGMAR1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |