Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 6/20 | 0.32 |
| ▸ | NPC1 | O15118 | 5/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7310564 | 0.99 | SMN1; SMN2 (0.33) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| SCHEMBL7317411 | 0.94 | SMN1; SMN2 (0.33) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| SCHEMBL7322049 | 0.92 | SMN1; SMN2 (0.39) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| Hydrochloric Acid SCHEMBL7311480 | 0.91 | RAB9A (0.38) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| SCHEMBL7313165 | 0.91 | RAB9A (0.40) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| SCHEMBL7372897 | 0.91 | RAB9A (0.39) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| SCHEMBL7323656 | 0.91 | NPC1 (0.32) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| Hydrochloric Acid SCHEMBL7313205 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| Hydrochloric Acid SCHEMBL7320309 | 0.91 | SMN1; SMN2 (0.39) | SMN1; SMN2GAAALDH1A1LMNATHRB | |
| SCHEMBL7314312 | 0.90 | SMN1; SMN2 (0.39) | SMN1; SMN2GAAALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |