Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | RXRG | P48443 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16897964 | 0.90 | KMT2A (0.73) | KMT2AMEN1TDP1SLC6A2SLC6A3 | |
| SCHEMBL6851170 | 0.90 | KMT2A (0.68) | KMT2AMEN1TDP1SLC6A2SLC6A3 | |
| SCHEMBL6653550 | 0.88 | KMT2A (0.50) | KMT2AMEN1MRGPRX4TDP1SLC6A2 | |
| SCHEMBL19504138 | 0.88 | TDP1 (0.68) | KMT2ATDP1SLC6A2SLC6A3LMNA | |
| SCHEMBL7420476 | 0.87 | LMNA (0.62) | KMT2AMEN1MRGPRX4LMNANR4A2 | |
| SCHEMBL7428565 | 0.87 | MEN1 (0.79) | KMT2AMEN1MRGPRX4NR4A2RXRA | |
| SCHEMBL6653024 | 0.86 | KMT2A (0.48) | KMT2AMEN1MRGPRX4TDP1SLC6A2 | |
| SCHEMBL16137683 | 0.85 | MEN1 (0.62) | KMT2AMEN1MRGPRX4NR4A2RXRA | |
| SCHEMBL14018084 | 0.84 | PARP10 (0.63) | KMT2AMEN1MRGPRX4NR4A2RXRA | |
| SCHEMBL6655185 | 0.84 | TDP1 (0.62) | KMT2AMEN1TDP1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5376655-A | Elastase inhibitor | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-12-27 | — | — | US | disclosed |
| US-5247084-A | Inhibitors of elastase | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-09-21 | — | — | US | disclosed |
| US-5077428-A | Antiinflammatory agents | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0222608-B1 | DERIVATIVES OF P-GUANIDINOBENZOIC ACID AND PHARMACEUTICAL AGENTS CONTAINING THEM AS ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1991-09-11 | — | — | EP | disclosed |
| US-4975464-A | ADMINISTERING DERIVATIVES OF P-GUANIDINOBENZOIC ACID | IMAKI KATSUHIRO (JP) | 1990-12-04 | — | — | US | disclosed |
| US-4843094-A | ELASTASE INHIBITOR | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-06-27 | — | — | US | disclosed |
| EP-0222608-A2 | Derivatives of p-guanidinobenzoic acid and pharmaceutical agents containing them as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 1987-05-20 | — | — | EP | disclosed |