Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.66 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.32 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7301546 | 0.93 | ITGB3 (0.63) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7306099 | 0.92 | ITGB3 (0.62) | ITGB3ITGA2BPRSS1 | |
| Hydrochloric Acid SCHEMBL7312195 | 0.92 | ITGB3 (0.64) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7277217 | 0.91 | ITGB3 (0.54) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7312835 | 0.91 | ITGB3 (0.67) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7303593 | 0.91 | ITGB3 (0.69) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7305244 | 0.90 | ITGB3 (0.66) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7312948 | 0.90 | ITGB3 (0.51) | ITGB3ITGA2BIRAK4 | |
| Hydrochloric Acid SCHEMBL7314901 | 0.89 | ITGB3 (0.69) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL7275270 | 0.88 | ITGB3 (0.75) | ITGB3ITGA2BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567966-B1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-09-02 | — | — | EP | claimed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | claimed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | claimed |
| EP-0567966-B1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-09-02 | — | — | EP | disclosed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |