Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.55 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | CASP1 | P29466 | 6/20 | 0.51 |
| ▸ | USP2 | O75604 | 4/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309420 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7319001 | 0.82 | PDE3B (0.49) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7316463 | 0.80 | PDE3B (0.54) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7306694 | 0.79 | PDE3B (0.61) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7306060 | 0.78 | PDE3B (0.65) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7313626 | 0.78 | PDE3B (0.65) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7316100 | 0.77 | PDE3B (0.51) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL5811108 | 0.77 | PDE3B (0.69) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7320321 | 0.77 | PDE3B (0.49) | ALDH1A1KDM4EHSD17B10HPGDGAA | |
| SCHEMBL7318197 | 0.77 | PDE3B (0.64) | ALDH1A1KDM4EHSD17B10HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |