SCHEMBL7311481

SCHEMBL7311481

O=C1NC2=Nc3c(Cl)cc(OCC(=O)N(CCO)C4CCCCC4)cc3CN2C1CO

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 20/20 0.51
PDE3A Q14432 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7311478 0.86 PDE3B (0.52) PDE3BPDE3A
SCHEMBL7311995 0.82 PDE3B (0.71) PDE3BPDE3A
SCHEMBL7310791 0.78 PDE3B (0.49) PDE3BPDE3A
SCHEMBL7307915 0.78 PDE3B (0.80) PDE3BPDE3A
SCHEMBL7305821 0.76 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7311105 0.74 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7310481 0.73 PDE3B (0.59) PDE3BPDE3A
SCHEMBL7315869 0.72 PDE3B (0.58) PDE3BPDE3A
SCHEMBL7307962 0.71 PDE3B (0.53) PDE3BPDE3A
SCHEMBL7313434 0.71 PDE3B (0.58) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed