Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313964 | 0.96 | MAPT (0.40) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL7311369 | 0.95 | MAPT (0.39) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL7309626 | 0.90 | SIRT5 (0.43) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL7308163 | 0.88 | SIRT5 (0.44) | MAPTALDH1A1SIRT5 | |
| Hydrochloric Acid SCHEMBL7311528 | 0.87 | SIRT5 (0.43) | MAPTALDH1A1SIRT5 | |
| SCHEMBL7317736 | 0.86 | MAPT (0.43) | MAPTALDH1A1HPGDKDM4EKMT2A | |
| SCHEMBL7317041 | 0.85 | MAPT (0.42) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL7321233 | 0.85 | MAPT (0.42) | MAPTALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL7313303 | 0.85 | PPARA (0.46) | MAPTALDH1A1SIRT5 | |
| SCHEMBL7318161 | 0.84 | ALB (0.47) | MAPTKMT2AMEN1SIRT5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |