SCHEMBL7312285

SCHEMBL7312285

CCCc1nc2c(C)cc(C(=N)N)cc2n1Cc1ccc(-c2ccccc2OC(=O)OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AGTR1 P30556 20/20 0.59
AGTR2 P50052 3/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7310912 0.92 AGTR1 (0.59) AGTR1AGTR2
Water SCHEMBL7304247 0.91 AGTR1 (0.58) AGTR1AGTR2
SCHEMBL9410724 0.89 AGTR1 (0.59) AGTR1AGTR2
SCHEMBL8847682 0.87 AGTR1 (0.66) AGTR1AGTR2
SCHEMBL9573017 0.85 AGTR1 (0.57) AGTR1AGTR2
SCHEMBL7310905 0.84 AGTR1 (0.76) AGTR1AGTR2
SCHEMBL9410713 0.84 AGTR1 (0.56) AGTR1AGTR2
Water SCHEMBL8847534 0.84 AGTR1 (0.75) AGTR1AGTR2
SCHEMBL9572850 0.82 AGTR1 (0.56) AGTR1AGTR2
SCHEMBL9572990 0.82 AGTR1 (0.54) AGTR1AGTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0566020-A1 Benzimidazoles, pharmaceutical compositions thereof and processes for their preparation Dr. Karl Thomae GmbH (DE) 1993-10-20 EP disclosed
EP-0502314-A1 Benzimidazol, medicaments containing them and process for their preparation Dr. Karl Thomae GmbH (DE) 1992-09-09 EP disclosed