Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312432 | 0.81 | PDE3B (0.45) | PDE3BPDE3AALDH1A1KDM4ELMNA | |
| SCHEMBL7308217 | 0.80 | PDE3B (0.68) | PDE3BPDE3AP2RY12 | |
| SCHEMBL7320355 | 0.78 | PDE3B (0.40) | PDE3BPDE3A | |
| SCHEMBL7303290 | 0.77 | PDE3B (0.71) | PDE3BPDE3AP2RY12 | |
| SCHEMBL7317488 | 0.77 | PDE3B (0.47) | PDE3BPDE3A | |
| SCHEMBL7313037 | 0.75 | PDE3B (0.46) | PDE3BPDE3AALDH1A1KDM4ELMNA | |
| SCHEMBL7320483 | 0.74 | PDE3B (0.46) | PDE3BPDE3A | |
| SCHEMBL7307703 | 0.74 | PDE3B (0.45) | PDE3BPDE3A | |
| SCHEMBL7320488 | 0.74 | PDE3B (0.45) | PDE3BPDE3AALDH1A1MEN1KMT2A | |
| SCHEMBL7312743 | 0.74 | PDE3B (0.63) | PDE3BPDE3AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |