Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305746 | 0.80 | PDE3B (0.42) | PDE3BPDE3ACNR1CNR2HDAC3 | |
| SCHEMBL7313658 | 0.76 | PDE3B (0.43) | PDE3BPDE3ACNR1CNR2 | |
| SCHEMBL7307444 | 0.76 | PDE3B (0.67) | PDE3BPDE3A | |
| SCHEMBL7318841 | 0.74 | PDE3B (0.65) | PDE3BPDE3A | |
| SCHEMBL7320488 | 0.72 | PDE3B (0.45) | PDE3BPDE3A | |
| SCHEMBL7316993 | 0.70 | MAPT (0.34) | PDE3BPDE3AHDAC3HDAC1HDAC2 | |
| SCHEMBL7304527 | 0.70 | PDE3B (0.57) | PDE3BPDE3A | |
| SCHEMBL7313764 | 0.70 | HDAC1 (0.34) | PDE3BPDE3AHDAC3BRD4BRD2 | |
| SCHEMBL7311790 | 0.66 | PDE3B (0.65) | PDE3BPDE3A | |
| SCHEMBL7319732 | 0.66 | PDE3B (0.42) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |