Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7745884 | 0.98 | SSTR4 (0.52) | SSTR4OPRM1OPRL1SCN9AMEN1 | |
| SCHEMBL7314168 | 0.94 | SSTR4 (0.54) | SSTR4OPRM1OPRL1SCN9AHPGD | |
| Hydrochloric Acid SCHEMBL7751607 | 0.93 | SSTR4 (0.53) | SSTR4OPRM1OPRL1SCN9AHPGD | |
| SCHEMBL7313301 | 0.93 | SSTR4 (0.56) | SSTR4OPRM1OPRL1SCN9AGAA | |
| Hydrochloric Acid SCHEMBL7750679 | 0.92 | SSTR4 (0.55) | SSTR4OPRM1OPRL1SCN9AGAA | |
| SCHEMBL6972395 | 0.82 | OPRM1 (0.50) | SSTR4OPRM1HPGDHDAC1POLB | |
| Hydrochloric Acid SCHEMBL7723494 | 0.81 | OPRM1 (0.48) | SSTR4OPRM1HPGDHDAC1POLB | |
| SCHEMBL8368922 | 0.80 | SSTR4 (0.42) | SSTR4MEN1MAPTKMT2AHDAC1 | |
| SCHEMBL29541999 | 0.80 | SSTR4 (0.55) | SSTR4OPRM1OPRL1SCN9AMAPT | |
| SCHEMBL4552161 | 0.80 | SSTR4 (0.49) | SSTR4OPRM1OPRL1SCN9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673928-A1 | Novel N-(3,4-dichlorophenyl-propyl)-piperidine derivatives as selective human NK3-receptor antagonists | SANOFI (FR) | 1995-09-27 | — | — | EP | disclosed |