Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | SLC33A1 | O00400 | 7/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL9256428 | 0.96 | PPARG (0.42) | PPARGSLC33A1ENPP1MBOAT4 | |
| SCHEMBL9254113 | 0.92 | PPARG (0.39) | PPARGSLC33A1ENPP1MBOAT4ESR2 | |
| SCHEMBL9250470 | 0.90 | SLC33A1 (0.45) | PPARGSLC33A1ENPP1 | |
| SCHEMBL9254787 | 0.89 | PPARG (0.46) | PPARGSLC33A1ENPP1MBOAT4GABRA1 | |
| SCHEMBL9253643 | 0.89 | PPARG (0.44) | PPARGSLC33A1ENPP1MBOAT4GABRA1 | |
| SCHEMBL9250123 | 0.88 | ESR2 (0.39) | PPARGSLC33A1ENPP1MBOAT4ESR2 | |
| SCHEMBL9249469 | 0.86 | ENPP1 (0.47) | ENPP1MBOAT4GABRA1GABRG2GABRB3 | |
| SCHEMBL9249571 | 0.86 | PPARG (0.42) | PPARGSLC33A1ENPP1MBOAT4GABRA1 | |
| SCHEMBL9258137 | 0.86 | PPARG (0.45) | PPARGSLC33A1 | |
| Hydrochloric Acid SCHEMBL7322883 | 0.85 | PPARG (0.44) | PPARGSLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |
| US-5231094-A | Cardiovascular disorders | SOCIETE ANONYME: LABORATOIRES UPSA (FR) | 1993-07-27 | — | — | US | disclosed |