Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.39 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SLC33A1 | O00400 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250470 | 0.90 | SLC33A1 (0.45) | PPARGENPP1SLC33A1 | |
| SCHEMBL7313334 | 0.89 | PPARG (0.44) | PPARGENPP1MBOAT4SLC33A1GABRA1 | |
| SCHEMBL9253643 | 0.89 | PPARG (0.44) | PPARGENPP1MBOAT4SLC33A1GABRA1 | |
| SCHEMBL9249571 | 0.86 | PPARG (0.42) | PPARGENPP1MBOAT4SLC33A1GABRA1 | |
| Diethylamine SCHEMBL9256428 | 0.85 | PPARG (0.42) | PPARGENPP1MBOAT4SLC33A1 | |
| SCHEMBL9253652 | 0.85 | PPARG (0.46) | PPARGENPP1MBOAT4ACHESLC33A1 | |
| SCHEMBL7320243 | 0.84 | PPARG (0.47) | PPARGACHE | |
| SCHEMBL9308857 | 0.83 | PPARG (0.46) | PPARG | |
| SCHEMBL9251529 | 0.81 | PPARG (0.44) | PPARGENPP1MBOAT4SLC33A1 | |
| SCHEMBL9252860 | 0.81 | PPARG (0.44) | PPARGENPP1SLC33A1GABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |