Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306672 | 0.84 | PDE3B (0.57) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7319001 | 0.82 | PDE3B (0.49) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7306908 | 0.76 | PDE3B (0.71) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7306759 | 0.74 | PDE3B (0.53) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7316100 | 0.74 | PDE3B (0.51) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7315797 | 0.73 | PDE3B (0.54) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7306732 | 0.72 | PDE3B (0.46) | PDE3BPDE3AP2RY12ALDH1A1CYP2D6 | |
| SCHEMBL7317542 | 0.71 | ALDH1A1 (0.54) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7312582 | 0.70 | ALDH1A1 (0.41) | PDE3BPDE3AP2RY12ALDH1A1KDM4E | |
| SCHEMBL7307899 | 0.70 | PDE3B (0.53) | PDE3BPDE3AP2RY12ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4277479-A | ANTI-ASTHMATIC, HYPOTENSIVE, ANTI-ULCER, ANTIINFLAMMATORY, VASODILATION, ENZYME INHIBITORS, ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |