Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
| ▸ | EDNRA | P25101 | 3/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7302537 | 0.95 | AGTR2 (0.44) | AGTR2 | |
| SCHEMBL7300928 | 0.94 | AGTR2 (0.47) | AGTR2EDNRAAGTR1 | |
| SCHEMBL7310154 | 0.93 | AGTR2 (0.47) | AGTR2EDNRAAGTR1 | |
| SCHEMBL7302104 | 0.92 | AGTR2 (0.41) | AGTR2EDNRAAGTR1 | |
| SCHEMBL7310133 | 0.90 | AGTR2 (0.44) | AGTR2AGTR1 | |
| SCHEMBL7309469 | 0.89 | AGTR2 (0.39) | AGTR2EDNRAAGTR1 | |
| SCHEMBL7306149 | 0.88 | AGTR2 (0.44) | AGTR2EDNRAAGTR1 | |
| SCHEMBL7306526 | 0.87 | AGTR2 (0.39) | AGTR2EDNRAAGTR1 | |
| SCHEMBL7300275 | 0.86 | AGTR2 (0.41) | AGTR2AGTR1 | |
| SCHEMBL7312844 | 0.86 | AGTR2 (0.41) | AGTR2EDNRAAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310927-A | Hypotensive agents; cognition activators; imidazolyl-2-aryl derivatives | GLAXO GROUP LIMITED (GB) | 1994-05-10 | — | — | US | claimed |
| EP-0514193-A1 | N-linked imidazolyl-methyl benzofuran derivatives with antihypotensive activity | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | claimed |
| US-5310927-A | Hypotensive agents; cognition activators; imidazolyl-2-aryl derivatives | GLAXO GROUP LIMITED (GB) | 1994-05-10 | — | — | US | disclosed |
| EP-0514193-A1 | N-linked imidazolyl-methyl benzofuran derivatives with antihypotensive activity | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |