Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314568 | 0.86 | F10 (0.48) | F10GRM2NAMPT | |
| SCHEMBL7458570 | 0.80 | NAMPT (0.43) | F10NAMPT | |
| SCHEMBL6489041 | 0.80 | GRM2 (0.41) | GRM2 | |
| SCHEMBL7458575 | 0.78 | NAMPT (0.42) | F10NAMPT | |
| SCHEMBL8799790 | 0.78 | GRM2 (0.57) | GRM2 | |
| SCHEMBL7543143 | 0.78 | GRM2 (0.57) | GRM2 | |
| SCHEMBL8798953 | 0.78 | GRM2 (0.57) | GRM2 | |
| SCHEMBL7300463 | 0.77 | GRM2 (0.49) | GRM2 | |
| SCHEMBL2290523 | 0.77 | GRM2 (0.51) | GRM2 | |
| SCHEMBL1711842 | 0.77 | GRM2 (0.51) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |