Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | CALML3 | P27482 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313752 | 0.86 | F10 (0.44) | F10GRM2NAMPT | |
| SCHEMBL7458570 | 0.85 | NAMPT (0.43) | F10NAMPT | |
| SCHEMBL7458575 | 0.83 | NAMPT (0.42) | F10NAMPT | |
| SCHEMBL8892459 | 0.79 | F10 (0.41) | F10NAMPT | |
| SCHEMBL20802077 | 0.77 | F10 (0.54) | F10MAOAMAOBNAMPTCALML3 | |
| SCHEMBL6763371 | 0.77 | MAPT (0.52) | MAOAMAOBNAMPT | |
| SCHEMBL6478216 | 0.77 | MAOA (0.47) | MAOAMAOBGRM2CALML3 | |
| SCHEMBL6763369 | 0.77 | MAPT (0.52) | MAOAMAOBNAMPT | |
| SCHEMBL8892282 | 0.77 | NAMPT (0.41) | NAMPT | |
| SCHEMBL7464219 | 0.77 | SIGMAR1 (0.41) | F10NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5627197-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-05-06 | — | — | US | disclosed |
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |