Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.60 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.42 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313848 | 1.00 | CYP4F2 (0.60) | CYP4F2CYP4A11ALDH1A1FFAR1MEN1 | |
| SCHEMBL7313853 | 1.00 | CYP4F2 (0.60) | CYP4F2CYP4A11ALDH1A1FFAR1MEN1 | |
| SCHEMBL24496702 | 0.88 | CYP4F2 (0.56) | CYP4F2CYP4A11ALDH1A1FFAR1MEN1 | |
| SCHEMBL29587184 | 0.88 | CYP4F2 (0.51) | CYP4F2CYP4A11ALDH1A1FFAR1MEN1 | |
| SCHEMBL10808822 | 0.87 | ALDH1A1 (0.47) | CYP4F2CYP4A11ALDH1A1MEN1KMT2A | |
| SCHEMBL12660944 | 0.86 | CYP4F2 (0.64) | CYP4F2CYP4A11ALDH1A1MEN1KMT2A | |
| SCHEMBL7082197 | 0.85 | CYP4F2 (0.55) | CYP4F2CYP4A11FFAR1MTNR1BPPARG | |
| SCHEMBL1019684 | 0.85 | CYP4F2 (0.62) | CYP4F2CYP4A11 | |
| SCHEMBL9838425 | 0.85 | CYP4F2 (0.62) | CYP4F2CYP4A11 | |
| SCHEMBL9837746 | 0.85 | CYP4F2 (0.62) | CYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684039-A | Chroman-2-ylmethylamino derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5670667-A | DOPAMINE INHIBITORS FOR PSYCHOLOGICAL DISORDERS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-09-23 | — | — | US | disclosed |