Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312215 | 0.99 | MAPT (0.44) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| SCHEMBL7308999 | 0.96 | MAPT (0.46) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| SCHEMBL7311275 | 0.95 | MAPT (0.45) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| SCHEMBL7315491 | 0.91 | MAPT (0.46) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| SCHEMBL7317426 | 0.91 | ALDH1A1 (0.46) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL7313878 | 0.90 | ALDH1A1 (0.45) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| SCHEMBL7318928 | 0.90 | MAPT (0.45) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL7312227 | 0.89 | MAPT (0.44) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| SCHEMBL7307761 | 0.88 | ALDH1A1 (0.47) | MAPTALDH1A1CYP3A4KDM4EALOX15 | |
| Hydrochloric Acid SCHEMBL7309003 | 0.86 | MAPT (0.46) | MAPTALDH1A1CYP3A4KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |