Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.92 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.85 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20703807 | 0.86 | NOTUM (1.00) | SMN1; SMN2KDM4ENOTUMRAB9ALMNA | |
| SCHEMBL6538920 | 0.83 | RAB9A (0.94) | SMN1; SMN2KDM4ENOTUMRAB9ALMNA | |
| SCHEMBL7323592 | 0.80 | RAB9A (1.00) | SMN1; SMN2KDM4ENOTUMRAB9ALMNA | |
| SCHEMBL6154686 | 0.79 | NOTUM (0.71) | SMN1; SMN2KDM4ENOTUMRAB9AMAPT | |
| SCHEMBL11338103 | 0.77 | KDM4E (0.65) | SMN1; SMN2KDM4ENOTUMRAB9ALMNA | |
| SCHEMBL2151432 | 0.76 | TSHR (0.69) | SMN1; SMN2TSHRCYP1A2CYP19A1CYP2C9 | |
| SCHEMBL17142884 | 0.76 | TSHR (0.69) | SMN1; SMN2TSHRCYP1A2CYP19A1CYP2C9 | |
| SCHEMBL17143201 | 0.76 | TSHR (0.69) | SMN1; SMN2TSHRCYP1A2CYP19A1CYP2C9 | |
| SCHEMBL18675930 | 0.76 | TSHR (0.79) | SMN1; SMN2KDM4ETSHRTP53CYP1A2 | |
| SCHEMBL11329045 | 0.75 | NOTUM (0.66) | SMN1; SMN2KDM4ENOTUMRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |