SCHEMBL731433

SCHEMBL731433

CCCCCCCCCCCCOP(=O)(CCCC)OCCCC

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 7/20 0.57
LPAR2 Q9HBW0 6/20 0.57
LPAR1 Q92633 3/20 0.57
CYP3A4 P08684 2/20 0.54
AKT1 P31749 2/20 0.46
LMNA P02545 1/20 0.46
ESR1 P03372 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CDC25A P30304 1/20 0.46
AGTR1 P30556 1/20 0.46
ADRA1A P35348 1/20 0.46
KCNH2 Q12809 1/20 0.46
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TSHR P16473 1/20 0.42
TERT O14746 1/20 0.41
UCHL3 P15374 1/20 0.41
MAPK14 Q16539 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11046059 1.00 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL1296828 1.00 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL1295541 1.00 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL1296681 1.00 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL9262129 1.00 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL23650045 1.00 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL11878700 1.00 LPAR3 (0.57) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL11668838 0.98 LPAR3 (0.59) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL7106488 0.98 LPAR3 (0.59) LPAR3LPAR2LPAR1CYP3A4AKT1
SCHEMBL9257620 0.98 LPAR3 (0.59) LPAR3LPAR2LPAR1CYP3A4AKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109456469-B Preparation method of high-fluidity cation modified copolyester 东华大学 2020-08-25 CN disclosed
EP-1443061-B2 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2012-10-31 EP disclosed
EP-2287210-B1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2012-07-18 EP disclosed
US-8138130-B2 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE COMPANY LLC (US) 2012-03-20 US disclosed
EP-1707616-B1 Fused-ring aromatic amine based wear and oxidation inhibitors for lubricants CHEVRON ORONITE CO (US) 2011-06-22 EP disclosed
EP-2287210-A2 Sulfurized polyisobutylene based wear and oxidation inhibitors Chevron Oronite Company LLC (US) 2011-02-23 EP disclosed
EP-1857474-B1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2010-09-22 EP disclosed
US-7414013-B2 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE COMPANY LLC (US) 2008-08-19 US disclosed
EP-1443061-B1 Sulfurized polyisobutylene based wear and oxidation inhibitors CHEVRON ORONITE CO (US) 2007-12-05 EP disclosed
EP-1857474-A2 Sulfurized polyisobutylene based wear and oxidation inhibitors Chevron Oronite Company LLC (US) 2007-11-21 EP disclosed
US-6096691-A Gear oil additive concentrates and lubricants containing them ETHYL CORPORATION (US) 2000-08-01 US disclosed
EP-0692012-B1 GEAR OIL COMPOSITIONS ETHYL CORP (US) 1998-07-15 EP disclosed
US-5571445-A Gear oil compositions ETHYL CORPORATION (US) 1996-11-05 US disclosed
EP-0693104-A4 GEAR OIL ADDITIVE CONCENTRATES AND LUBRICANTS CONTAINING THEM ETHYL CORP (US) 1996-03-27 EP disclosed
EP-0692012-A4 1996-01-24 EP disclosed
EP-0693104-A1 GEAR OIL ADDITIVE CONCENTRATES AND LUBRICANTS CONTAINING THEM ETHYL CORPORATION (US) 1996-01-24 EP disclosed
EP-0692012-A1 GEAR OIL COMPOSITIONS ETHYL CORPORATION (US) 1996-01-17 EP disclosed
WO-1994024233-A1 GEAR OIL ADDITIVE CONCENTRATES AND LUBRICANTS CONTAINING THEM ETHYL CORPORATION (US) 1994-10-27 WO disclosed
US-5358650-A Gear oil compositions ETHYL CORPORATION (US) 1994-10-25 US disclosed
WO-1994022990-A1 GEAR OIL COMPOSITIONS ETHYL CORPORATION (US) 1994-10-13 WO disclosed