⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1053342 | 0.95 | — | — | |
| SCHEMBL15919212 | 0.84 | — | — | |
| SCHEMBL567476 | 0.67 | TRIM24 (0.38) | — | |
| SCHEMBL567477 | 0.67 | TRIM24 (0.38) | — | |
| SCHEMBL12262994 | 0.67 | — | — | |
| SCHEMBL567479 | 0.67 | TRIM24 (0.38) | — | |
| SCHEMBL605008 | 0.60 | — | — | |
| SCHEMBL1425898 | 0.57 | — | — | |
| SCHEMBL1426215 | 0.57 | TRIM24 (0.38) | — | |
| SCHEMBL1426651 | 0.57 | TRIM24 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635377-A | Ketohexokinase inhibitors and uses thereof | 四川海思科制药有限公司 | 2023-08-22 | — | — | CN | claimed |
| CN-116535396-A | Ketohexokinase inhibitors and uses thereof | 海思科医药集团股份有限公司 | 2023-08-04 | — | — | CN | claimed |
| CN-116354932-A | Pyrimidine derivative, preparation method and application thereof | 海思科医药集团股份有限公司 | 2023-06-30 | — | — | CN | claimed |
| EP-0296892-A2 | Novel linear derivatives of arginine vasopressin antagonists | Medical College of Ohio (US) | 1988-12-28 | — | — | EP | claimed |
| CN-116635377-A | Ketohexokinase inhibitors and uses thereof | 四川海思科制药有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116535396-A | Ketohexokinase inhibitors and uses thereof | 海思科医药集团股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| CN-116354932-A | Pyrimidine derivative, preparation method and application thereof | 海思科医药集团股份有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-20220204473-A1 | COMPOUND AS IRAK INHIBITOR | WUHAN CREATERNA SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2022-06-30 | — | — | US | disclosed |
| CN-114284555-A | Low-temperature electrolyte and lithium ion battery containing same | 广东比沃新能源有限公司 | 2022-04-05 | — | — | CN | disclosed |
| EP-3889150-A1 | COMPOUND SERVING AS IRAK INHIBITOR | Shanghai Meiyue Biotech Development Co., Ltd. (CN) | 2021-10-06 | — | — | EP | disclosed |
| CN-113227079-A | Compound as IRAK inhibitor | 上海美悦生物科技发展有限公司 | 2021-08-06 | — | — | CN | disclosed |
| CN-109748915-B | Inhibitors of influenza virus replication and methods of use and uses thereof | 广东东阳光药业有限公司 | 2021-03-26 | — | — | CN | disclosed |
| CN-111362920-A | Compound as IRAK inhibitor | 上海美悦生物科技发展有限公司 | 2020-07-03 | — | — | CN | disclosed |
| US-5217982-A | Compounds having antihypertensive properties | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1993-06-08 | — | — | US | disclosed |
| US-5055448-A | Diuretics | MEDICAL COLLEGE OF OHIO (US) | 1991-10-08 | — | — | US | disclosed |
| US-5055448-A | Diuretics | MEDICAL COLLEGE OF OHIO (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0296892-A3 | NOVEL LINEAR DERIVATIVES OF ARGININE VASOPRESSIN ANTAGONISTS | Medical College of Ohio (US) | 1990-07-11 | — | — | EP | disclosed |
| EP-0296892-A2 | Novel linear derivatives of arginine vasopressin antagonists | Medical College of Ohio (US) | 1988-12-28 | — | — | EP | disclosed |