Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | EBP | Q15125 | 2/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313731 | 0.92 | CACNA1B (0.38) | EBPSIGMAR1CACNA1BCHRM2CHRM3 | |
| SCHEMBL7319369 | 0.92 | EPHX1 (0.34) | EPHX1EBPSIGMAR1CACNA1BSCN9A | |
| SCHEMBL7316004 | 0.90 | EPHX1 (0.37) | EPHX1EBPSIGMAR1 | |
| SCHEMBL7310134 | 0.89 | EBP (0.37) | EBPSIGMAR1CACNA1BCHRM2CHRM3 | |
| SCHEMBL7306036 | 0.89 | EBP (0.41) | EBPSIGMAR1CACNA1BCHRM3 | |
| SCHEMBL7305376 | 0.88 | EBP (0.37) | EBPSIGMAR1CACNA1BCHRM3 | |
| SCHEMBL7316806 | 0.88 | EBP (0.37) | EBPSIGMAR1CACNA1BCHRM2CHRM3 | |
| SCHEMBL7317745 | 0.88 | EBP (0.37) | EBPSIGMAR1CACNA1BCHRM2CHRM3 | |
| SCHEMBL7317234 | 0.88 | EBP (0.37) | EBPSIGMAR1CACNA1BSCN9ACHRM2 | |
| SCHEMBL7311104 | 0.87 | EBP (0.35) | EPHX1EBPSIGMAR1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |