Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 5/20 | 0.64 |
| ▸ | ANPEP | P15144 | 4/20 | 0.64 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.64 |
| ▸ | ECE1 | P42892 | 6/20 | 0.60 |
| ▸ | PYGB | P11216 | 1/20 | 0.60 |
| ▸ | IL1RN | P18510 | 2/20 | 0.57 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP14 | P50281 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306489 | 0.96 | ERAP2 (0.68) | ERAP2ANPEPERAP1ECE1PYGB | |
| SCHEMBL7304171 | 0.92 | ECE1 (0.63) | ERAP2ANPEPERAP1ECE1PYGB | |
| SCHEMBL7307608 | 0.91 | ERAP2 (0.62) | ERAP2ANPEPERAP1ECE1PYGB | |
| SCHEMBL7315378 | 0.91 | ECE1 (0.63) | ERAP2ANPEPERAP1ECE1PYGB | |
| SCHEMBL7306818 | 0.89 | ERAP1 (0.59) | ERAP2ANPEPERAP1ECE1PYGB | |
| SCHEMBL7307671 | 0.88 | ERAP2 (0.58) | ERAP2ANPEPERAP1ECE1PYGB | |
| SCHEMBL17813732 | 0.87 | PYGB (0.69) | ERAP2ANPEPERAP1ECE1PYGB | |
| SCHEMBL7327655 | 0.87 | PYGB (0.69) | ERAP2ANPEPERAP1ECE1PYGB | |
| SCHEMBL7309353 | 0.86 | ERAP2 (0.58) | ERAP2ANPEPERAP1ECE1IL1RN | |
| SCHEMBL14223176 | 0.85 | ANPEP (0.58) | ERAP2ANPEPERAP1ECE1IL1RN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380921-A | Enzyme inhibitors for endothelin converting enzyme for cardiovascular disorders and atherosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0623625-A1 | Aminophosphonic acid derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |