Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.37 |
| ▸ | APLNR | P35414 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | MERTK | Q12866 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250971 | 0.91 | PPARG (0.46) | PPARGESR2AGTR1AGTR2APLNR | |
| SCHEMBL7310723 | 0.85 | PPARG (0.45) | PPARGESR2 | |
| SCHEMBL7313672 | 0.84 | PPARG (0.46) | PPARGESR2AGTR1AGTR2APLNR | |
| SCHEMBL9254593 | 0.83 | PPARG (0.47) | PPARGAGTR1AGTR2 | |
| SCHEMBL7311768 | 0.82 | PPARG (0.46) | PPARG | |
| SCHEMBL9256457 | 0.81 | PPARG (0.46) | PPARGESR2AGTR1AGTR2APLNR | |
| SCHEMBL9256665 | 0.81 | PPARG (0.46) | PPARGESR2AGTR1AGTR2APLNR | |
| SCHEMBL9257368 | 0.80 | PPARG (0.44) | PPARGESR2AGTR1AGTR2APLNR | |
| SCHEMBL9256269 | 0.79 | PPARG (0.44) | PPARGESR2AGTR1AGTR2APLNR | |
| Diethylamine SCHEMBL9256272 | 0.79 | PPARG (0.44) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |
| US-5231094-A | Cardiovascular disorders | SOCIETE ANONYME: LABORATOIRES UPSA (FR) | 1993-07-27 | — | — | US | disclosed |