Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SLC33A1 | O00400 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9254593 | 0.91 | PPARG (0.47) | PPARGAGTR1AGTR2SLC33A1 | |
| SCHEMBL9256457 | 0.89 | PPARG (0.46) | PPARGAGTR1AGTR2ESR2GRIA2 | |
| SCHEMBL9257368 | 0.87 | PPARG (0.44) | PPARGAGTR1AGTR2ESR2APLNR | |
| SCHEMBL9256269 | 0.86 | PPARG (0.44) | PPARGAGTR1AGTR2ESR2APLNR | |
| SCHEMBL9256213 | 0.85 | PPARG (0.43) | PPARGAGTR1AGTR2APLNRACHE | |
| SCHEMBL9253637 | 0.85 | PPARG (0.43) | PPARGAGTR1AGTR2ESR2 | |
| SCHEMBL7311768 | 0.84 | PPARG (0.46) | PPARGSLC33A1 | |
| SCHEMBL9260088 | 0.81 | PPARG (0.47) | PPARGAGTR1AGTR2ESR2APLNR | |
| SCHEMBL7315124 | 0.81 | PPARG (0.47) | PPARGAGTR1AGTR2ESR2GRIA2 | |
| Diethylamine SCHEMBL9256272 | 0.81 | PPARG (0.44) | PPARGSLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5387747-A | Used in the treatment and prevention of cardiovascular diseases: hypertension, cardiac insufficiency and atherosclerosis | LABORATOIRES UPSA (FR) | 1995-02-07 | — | — | US | disclosed |