Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 16/20 | 0.68 |
| ▸ | F2 | P00734 | 6/20 | 0.68 |
| ▸ | KLK1 | P06870 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.37 |
| ▸ | TMPRSS15 | P98073 | 10/20 | 0.37 |
| ▸ | ACR | P10323 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7303395 | 0.94 | PRSS1 (0.68) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL7315733 | 0.88 | PRSS1 (0.60) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL7313214 | 0.87 | PRSS1 (0.59) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL7316976 | 0.85 | PRSS1 (0.68) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL7312697 | 0.83 | PRSS1 (0.69) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3245051 | 0.81 | PRSS1 (1.00) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL7311244 | 0.81 | PRSS1 (1.00) | PRSS1F2KLK1KDM4EMEN1 | |
| SCHEMBL3239639 | 0.81 | PRSS1 (0.76) | PRSS1F2KLK1KDM4EMEN1 | |
| Acetic Acid SCHEMBL7312877 | 0.80 | PRSS1 (0.96) | PRSS1F2KLK1KDM4EMEN1 | |
| Acetic Acid SCHEMBL7311943 | 0.80 | PRSS1 (0.96) | PRSS1F2KLK1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5432178-A | Substituted benzoic acid esters; use to prevent or treat inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis or multiple organ failure | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |