Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 10/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 9/20 | 0.58 |
| ▸ | IL1RN | P18510 | 4/20 | 0.58 |
| ▸ | ANPEP | P15144 | 3/20 | 0.56 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.52 |
| ▸ | PYGB | P11216 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP9 | P14780 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MMP14 | P50281 | 2/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | NMBR | P28336 | 1/20 | 0.50 |
| ▸ | ECE1 | P42892 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310121 | 0.94 | ERAP1 (0.63) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL7358374 | 0.87 | NMBR (0.61) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL7353371 | 0.85 | ERAP1 (0.53) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL7313093 | 0.85 | ERAP1 (0.58) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL7307671 | 0.83 | ERAP2 (0.58) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL7356513 | 0.82 | ERAP1 (0.50) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL7356800 | 0.81 | ERAP1 (0.53) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL8200899 | 0.80 | ERAP1 (0.67) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL4843187 | 0.80 | ERAP1 (0.55) | ERAP1ERAP2IL1RNANPEPLNPEP | |
| SCHEMBL7313098 | 0.79 | ERAP1 (0.60) | ERAP1ERAP2IL1RNANPEPLNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5380921-A | Enzyme inhibitors for endothelin converting enzyme for cardiovascular disorders and atherosclerosis | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-01-10 | — | — | US | disclosed |
| EP-0623625-A1 | Aminophosphonic acid derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-11-09 | — | — | EP | disclosed |